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Its a naturally occurring compound whose secretion occurs in the bloodstream

[PubMed: 1411543] 98

Polymorphisms of the -opioid receptor gene influence cerebral pain processing in fibromyalgia

Subsequent secondary-source reviews have proposed candidate interactions modulation of GABAergic and glutamatergic tone, possible NMDA-receptor involvement, peripheral 1-adrenergic effects but these have not been replicated in primary studies that establish direct binding or saturable transduction at a defined receptor

[4] This is supported by a study of resistance-trained athletes showing that 2g per day of l-carnitine l-tartrate may have helped increase oxygen delivery into the muscle cells themselves

Asian J Androl (2003) 5(3):23142