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Effects of exercise on mitochondrial content and function in aging human skeletal muscle

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Ismail Kimji, MD, FRCPC, fellow of the Royal College of Physicians and Surgeons of Canada, reviewed the clinical statements, safety protocols, contraindication lists, and protocol guidance

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Human Cu/Zn superoxide dismutase (SOD1) overexpression in mice causes mitochondrial vacuolization, axonal degeneration, and premature motoneuron death and accelerates motoneuron disease in mice expressing a familial amyotrophic lateral sclerosis mutant SOD1

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