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We scanned the specimen in multiple areas and took into account the average results from all the pictures

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8.4 Adjunctive application of probiotics and synbiotics 8.4.1 Evidence hierarchy in probiotic/synbiotic interventions for DKD The therapeutic potential of probiotics and synbiotics in DKD management is supported by a hierarchical body of evidence spanning mechanistic studies to clinical trials

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J Clin Med (2020) 9

467 Studies using Zip13-KO mice have shown elevated levels of the cardiac fibrosis marker Col1a1 and the vascular inflammation-related gene eNOS, indicating the physiological importance of ZIP13 in maintaining cardiovascular homeostasis by resolving inflammation and stress response