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Bakers oncologist at Saint Francis Hospital and Medical Center referred her to a clinical trial at UConn Health involving two immunotherapy drugs: the FDA-approved Keytruda (pembrolizumab) from Merck & Co., credited with successfully treating former President Jimmy Carters melanoma

Bostan AC, Dum RP, Strick PL

Presence of significantly higher level of 8-OHdG in cancer DNA samples with AA-genotypes suggested that metabolic activation of RAN/tobacco in the oral cavity could produce a variety of toxic substances which induce various damages 42,43 including 8-OHdG 44

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