GHK-Cu (Glycyl-L-Histidyl-L-Lysine Copper) is a naturally occurring copper-binding peptide found in human plasma, saliva, and tissue
In vivo: 50-100 mg/kg (rodents) for robust NNMT inhibition 2
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Several iterations between auto- and manual-refinements were conducted for optimisation
Wrinkle Reduction One randomised, double-blind clinical trial found over 30% improvement in wrinkles in 8 weeks, compared to both an alternative peptide complex (Matrixyl 3000) and a control serum
Dried metabolite extracts were resuspended in 100 L of LCMS-graded water following microcentrifugation for 5 minutes at 21,000 xg at 4 C to pellet any remaining insoluble debris