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Some studies point out the role of the bacteriophages and the virome in IBD pathogenesis, although this field has not been well studied yet (88, 89)

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Whole-blood histamine, SAM, SAH, methionine, homocysteine, symptoms and nutrient response can provide more useful information than an MTHFR result alone

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If this theory is true, the idea is that because the immune and nervous systems are so energetically demanding, the body will eventually deplete in the nutrients and co-factors required for proper energy production, which drives a lot of the classic symptoms like fatigue, brain fog, rapid heart rate and blood pressure changes, and exercise intolerance

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