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Mast Cell Activation Syndrome Treatment Conventional treatment for mast cell activation syndrome generally involves the use of pharmaceutical and over-the-counter medications to alleviate symptoms, such as the following medications: Epinephrine (such as an EpiPen) for severe reactions First generation H1 blockers diphenhydramine (Benadryl) and hydroxyzine (Vistaril) Second generation H1 blockers, including loratadine (Claritin), cetirizine (Zyrtec), and fexofenadine (Allegra) H2 blockers, such as ranitidine (Zantac) and famotidine (Pepcid) Aspirin, to block production of prostaglandin D2 and reduce flushing

Talk with a clinician to determine which medication is right for youthe choice is often driven by ones medical history, total weight loss goals, and insurance coverage

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The best way to find out what your body specifically needs is to look at your unique lifestyle and goals

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The overproduction of ECM leads to fibrosis and causes progressive organ destruction as seen in patients with prolonged CP [29]