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Any claims about synergistic fat-loss effects from combining these agents are not supported by peer-reviewed clinical evidence

95% CI, 0.82-0.99) (33)

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Because DSIP is a small peptide that acts on the central nervous system and is degraded relatively quickly in plasma (for example, one study reported a half-life of ~78 minutes in human plasma)

As noted by the Alzheimers Drug Discovery Foundation (ADDF), the bulk of research involving epithalamin and epithalon has been conducted in Russia (or formerly, the Soviet Union) and has not been subject to independent confirmation [1]

In general, the endolymph has a higher osmolality than the perilymph