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When oxidative stress occurs, it damages neurons, disrupts signaling, and contributes to the progression of neurodegenerative disorders such as: Alzheimers disease Parkinsons disease Multiple sclerosis (MS) Amyotrophic lateral sclerosis (ALS) Over time, excessive oxidative damage impairs mitochondrial function the energy center of brain cells and accelerates neuronal decline

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As well, plasma homocysteine level predicts the clinical outcomes in PD patients (Zhong et al

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