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Rat blood serum samples were pre- equilibrated at 37C and then (50g) of each drug solution was added to 90 of rat serum in 1 .5mL Eppendorf tube maintained at 37C

In aged animal models, Epithalon treatment has been associated with preserved spatial memory, improved learning performance, and protection against age-related neuronal loss in key brain regions

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Journal of Trace Elements in Medicine and Biology

doi: 10.1073/pnas.0701549104 54 ZenattiPPRibeiroDLiWZuurbierLSilvaMCPaganinMet al

10.1210/er.2009-0024 86 MariniH.PolitoF.AltavillaD.IrreraN.MinutoliL.CalM.et al (2010)