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Thus, while the presence of 3-thiomethylindole would be likely to be a true product resulting from processing an endogenously formed glutathionylated detoxification product, the observed polysulfides would be most likely maintained at very low levels in planta , or only produced under conditions of oxidative stress

We hypothesized that high 15LO1, PEBP1, and GPX4 activity drives abnormal asthmatic redox biology, evidenced by lower bronchoalveolar lavage (BAL) fluid and intraepithelial cell GSH:oxidized GSH (GSSG) ratios, to enhance type 2 (T2) inflammatory responses

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[DOI] [PMC free article] [PubMed] [Google Scholar] [61].Waisman A, Ruiz PJ, Israeli E