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Greff D, Juhsz AE, Vncsa S, Vradi A, Sipos Z, Szinte J, et al

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Specifically, it inhibits HIF-1-mediated aberrant activation of PDK2 while promoting LONP1-dependent selective proteasomal degradation of PDK2, thereby restoring PDH activity and enhancing ATP production [82]

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It is specifically characterized by inflammation, demyelination, and neuronal loss and manifests with a range of neurological symptoms including numbness, tingling, vision impairment, cognitive impairment, and bladder and bowel dysfunction (Tafti et al., 2024)

Wegweisende ITP-Studie: Rapamycin verlngert die Lebensdauer von Musen auch bei sptem Behandlungsbeginn