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doi: 10.1016/j.molbiopara.2009.12.011, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 10.Yin J, Ren W, Yang G, Duan J, Huang X, Fang R, et al

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A consensus of the literature suggests that when there is a dysfunction in the brain reward cascade, especially in the dopamine system, causing a low or hypo-dopaminergic trait, the brain may require dopamine individuals to avoid unpleasant feelings (8, 9)

( b ) QuPath quantification of TOM20 and VDAC2 in tumour and stromal segments within AKP tumours 5FU, where each dot represents mean staining per mouse

People can also have 'normal' levels of B12 in their blood, but be symptomatic - this is known as a functional B12 deficiency

Characterization of a delta electroencephalogram-sleep-inducing peptide DSIP: a review of its functional significance