Deacon S, Arendt J
70 HP 130 AOD-9604 HGH Fragment 176-191 Lipolytic ALIASES AOD-9604, AOD9604, hGH(176-191), Tyr-hGH(177-191) CLASS Synthetic growth-hormone C-terminal fragment lipolytic candidate FORMULA CHNOS SEQUENCE 16-residue fragment corresponding to hGH(177-191) with N-terminal Tyrosine addition HALF-LIFE Short (minutes) plasma ROUTES Subcutaneous (Phase 2 obesity) Oral (food-supplement contexts in some jurisdictions) MECHANISM OF ACTION Synthetic 15-amino-acid fragment of human growth hormone (residues 176-191)
The copper ion confers catalytic activity: GHK acts as a copper chaperone, delivering Cu to cuproenzymes including superoxide dismutase 1 (SOD1), cytochrome c oxidase (Complex IV), lysyl oxidase (LOX), and ceruloplasmin
It is a contract manufacturer of peptide active ingredients in North Augusta, South Carolina, with FDA-inspected cGMP facilities and a $121.9 million expansion to bring more peptide production back to US soil by 2027
Data from the Phase III MATISSE trial supported the FDAs approval
No commercial antibody kits for BPC-157 are available, so cross-reactivity is negligible
