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Hedgehog signaling in animal development: paradigms and principles

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Photoaging, a major component of extrinsic aging, induces notable structural changes in the skin, such as shortening and thickening of collagen fibers, damage to elastic fibers, loss of type I collagen, and alterations in the ratio of collagen types within the dermis

10.3390/ijms18040852 Int

Research is starting to back this up