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Poor oral bioavailability it breaks down quickly in stomach acid, often requiring subcutaneous injections

Every number is derived and shown in the reconstitution section below

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A., Corash, L

Notably, the modulation of the Nrf2/HO-1 axis and associated metabolic pathways observed herein could also be relevant in sFlt-1-driven pathology, where oxidative stress and vascular dysfunction play central roles

Because patients with methemoglobinemia have normal amounts of dissolved O 2 in their blood, they have normal PaO 2 despite the low O 2 saturation on pulse oximetry, and the calculated O 2 saturation of Hb seems to be falsely elevated