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The current NICE guidance on B12 and folate deficiency sets this out clearly

Below: what 5-Amino-1MQ is, the NNMT/NAD+ mechanism behind it, the benefits research points to, oral vs injection, side effects and what's still unknown, why medical-grade sourcing matters, and how to find out if it's right for you

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Check out this paper from 1992: If the indiscriminate dumping of industrial cyanide waste continues unchecked with the inherent risk of pollution of food and water supplies there may well come a time when more widespread chronic cyanide neurotoxicity occurs in the Western hemisphere from a dietary source in persons with a genetic or acquired error of cyanide or vitamin B12 metabolism

What Are the Benefits of Vitamin B12 Injections