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The addition of GSH or expression of Grxs 1 and 2 significantly improves mutant SOD1 solubility in cell culture, whereas reducing the levels of intracellular GSH decreases SOD1 solubility, suggesting that GSH reduction promotes the aggregation of mutant SOD1 (Guareschi et al., 2012)

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Treatment for fracture healing typically runs three to nine months, though the maximum approved treatment duration is 24 months cumulative lifetime use

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Interestingly, erythropoietin exerted an antieryptotic effect, which protected against the prooxidant effect of aluminum [426]