Rathinam ML, Watts LT, Narasimhan M, Riar AK, Mahimainathan L, Henderson GI
How MSCs May Influence Autism Biology In preclinical models, MSC therapy has been associated with: Reduced neuroinflammation Decreased microglial activation Increased production of neurotrophic factors Enhanced synaptic plasticity Improved neuronal survival In mouse models of autism, MSC treatment has been linked to improvements in social interaction and reductions in repetitive behaviors
Peternel , Bele M, Gaberc-Porekar V, Menart V
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The broad distribution in brain of the processes regulating oxidative stress and mediating glutamatergic neurotransmission may explain the wide range of disorders in which both have been implicated
The evaluation of compounds such as CoQ10, DHEA, and Cleo-20 T3 could potentially increase the levels of ferredoxin 1 (FDX1), a key regulator of mitochondrial TCA cycle activity and electron transport chain efficiency, thereby mitigating lipid peroxidation and apoptosis in oocytes (Serrano et al., 2022)
