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Triple agonists with GLP1, GIP and glucagon Given the efficacy and benefits of the dual GLP-1/GIP RA tirzepatide and the dual GLP-1/glucagon RA, a triple agonist targeting all three receptors (GLP-1/GIP/glucagon) may result in superior WL and glycaemic control than dual agonists

It is also necessary to clarify the interconnectivity between disparate pathways within the internal milieu of the mitochondrial quality control system, to analyze the role of mitochondria and neurons in modulating the functionality of the brain and central nervous system, and to propose novel concepts and methodologies for the early diagnosis, prevention, and treatment of neurodegenerative diseases

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