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This means that the ligaments response to loading is not only dependent on the magnitude of the load but also on the rate at which the load is applied and the duration of the load

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These beneficial effects manifested with altered gene expression, including genes that increased ( Egr, Nos3, Srf, and Kras ) and genes that decreased ( Egr1, Vegfr2, and Plc ), while Akt1 remained unchanged in the inferior caval vein, the right ovarian vein and the left ovarian vein (Vukojevic et al., 2018)

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