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The MS spectra were recorded on an VelosPro IonTrap (Thermo Scientific) with an AdvanceBio Desalting-RP, 2.1 2.5 mm column (Agilent Technologies) and a gradient of the mobile phase A (0.1 % formic acid in water) to B (0.1 % formic acid in acetonitrile)

Baeyens N, Bandyopadhyay C, Coon BG, Yun S, Schwartz MA (2016) Endothelial fluid shear stress sensing in vascular health and disease

These findings underscore substantial disruptions in lipid metabolism in MS and highlight the role of various fatty acids in modulating Treg cell function and regulating the inflammatory milieu in this disease

The fluid itself addresses dehydration, which on its own can cause fatigue and headaches, as MedlinePlus notes

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