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Neuronal excitation, social stress, and altered metabolic states have been shown to modulate lactylation levels in neural tissues (Jia et al., 2021

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[PubMed: 1972496] (Retrospective analysis of 100 patients with acetaminophen induced acute liver failure found lower mortality in those receiving N-acetylcysteine [NAC] 10-36 hours after overdose than controls [37% vs 58%], suggesting beneficial effects of NAC even if given somewhat late)

Groups of 50 male and 50 female B6C3Fl mice were given dichlorvos (dissolved in corn oil) by oral gavage daily for 2 years

Store in a cool, dark place away from direct sunlight and out of reach of children