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Expression of the GPX6 gene is restricted to the olfactory epithelium

The legal line has not changed even as the regulatory picture evolves

For example, researchers have used crisantaspase and glutamine synthetase inhibitor methionine-L-sulfoximine (MSO) to deplete glutamine, which significantly impairs the growth of human hepatocellular carcinoma xenografts (48)

"Eye Health Statistics at a Glance" (PDF)

Since HEDS contains no glutathione moiety, alterations at the scaffold site could provide further insights regarding GSSEtOH as a potential reaction intermediate