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Bioavailability remains a major translational challenge for oral curcumin, which undergoes rapid metabolism and shows limited systemic exposure unless delivered through optimized formulations (e.g., liposomes, nano-phytosomes)

Preservative: Bac water contains benzyl alcohol to prevent bacterial growth

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Buddhala C, Campbell MC, Perlmutter JS, Kotzbauer PT (2015) Correlation between decreased CSF -synuclein and A1-42 in Parkinson disease

Additionally, the deposition of laminin, a key component of the basement membrane crucial for vascular integrity, further underscored the vascular perturbations characteristic of EAE (Roscoe and Welsh 2009)

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