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Product Details Table Molecular Structure The molecular structure of GHK-Cu has been studied in depth by methods such as X-ray crystallography, electron paramagnetic resonance spectroscopy, X-ray absorption broad spectrum, PMR spectroscopy and titration
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doi: 10.1172/jci.insight.165356 202 GirisaSAswaniBSManickasamyMKHegdeMAlqahtaniMSAbbasMet al
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The first two bind to the xenobiotic response element (XRE) sequences, while the last binds to the NF-B binding site in the NFE2L2 promoter, inducing its transcription [171,172,173,174], with a consequent increase of NFE2L2 mRNA available within the cell
Moreover, the literature has shown that changes in MET are related to anti-cancer resistance in some cancers, for example, non-small cell lung cancer (NSCLC) and colorectal cancer (CRC)
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