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61 One of the most well-known studies of TPE, the double-blind placebo-controlled AD management by albumin replacement (AMBAR) trial, hypothesized that withdrawing plasma might flush A plaque from the brain into the plasma where it could be removed, thereby reducing AD signs and symptoms

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PfGrx C32S/C88S is the previously characterized monothiol mutant of PfGrx

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However, if serum cobalamin concentration is within the normal range, treatment should be continued at least monthly and the owner should be forewarned that clinical signs may recur sometime in the future