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10.1002/cpt.2533 Clin

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A systematic analysis identified three research (two randomized controlled trials and one cell culture study) involving women with polycystic ovary syndrome getting therapy with assisted reproductive technologies [182]

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This means that the more estrogens are conjugated by sulphation or glucuronidation, the lower the conversion into estrogen quinones, which can subsequently be converted into glutathione conjugates or lead to the formation of DNA adducts