Alterations in gut microbiota and plasma metabolites in patients with generalized anxiety disorder: a multi-omics study
Head MD, Guidelines Consortium NST, members C, Maniakas A, Jozaghi Y, Zafereo ME , Sturgis EM, Su SY, Gillenwater AM, Gidley PW, Lewis CM, Diaz E, Goepfert RP, Kupferman ME, Gross ND, Hessel AC, Pytynia KB, Nader ME, Wang JR, Lango MN, Kiong KL, Guo T, Zhao X, CMKL Y, Appelbaum E, Alpard J, Garcia JA, Terry S, Flynn JE, Bauer S, Fournier D, Burgess CG, Wideman C, Johnston M, You C, De Luna R, Joseph L, Diersing J, Prescott K, Heiberger K, Mugartegui L, Rodriguez J, Zendehdel S, Sellers J, Friddell RA, Thomas A, Khanjae SJ, Schwarzlose KB, Chambers MS, Hofstede TM, Cardoso RC, Wesson RA, Won A, Otun AO, Gombos DS, Al-Zubidi N, Hutcheson KA, Gunn GB, Rosenthal DI, Gillison ML, Ferrarotto R, Weber RS, Hanna EY, Myers JN, Lai SY
In some cases, fulminant liver failure may occur
But excess animal protein and high calcium supplement intake can raise stone risk for some people
Combination strategies also warrant exploration, including co-administration of apigenin and ellagic acid or their use alongside standard therapies such as metformin or letrozole to enhance efficacy and reduce drug-related side effects
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