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*Correspondence: Antonio Kokot, [email protected]

The reconstitution math is similar, but KLOW adds KPV as a fourth anti-inflammatory peptide that GLOW does not contain

Rigorous studies are still needed to confirm whether these peptides deliver consistent results in humans

Further analysis of signaling pathways confirmed that PD effectively upregulated endogenous TGF-/Nodal signaling and downstream Smad2/3 transduction, while concurrently downregulating BMP signaling, leading to robust DE formation