Puts, Stewart H
Riboflavin may be particularly helpful for people with the MTRR G allele.[ref] Additionally, studies show that riboflavin is particularly effective in people who are homozygous for MTHFR C677T (AA genotype).[ref] Related article: MTR, MTRR and more about B12 The B vitamins together: B-complex for the win Many studies show that a combination of folate, riboflavin, and/or vitamin B6 is very effective for lowering homocysteine.[ref][ref] Betaine or choline: Methyl groups to remethylate homocysteine can also be supplied by betaine (also called TMG) or choline in the diet.[ref] Beets are a good source of betaine, and eggs are rich in choline
Glutathione is not recommended for pregnant or breastfeeding individuals, or those with known allergies to glutathione or its component amino acids
Histopathological analysis further revealed that high expression of GSTA1 in mouse livers (Figure 4F, GSTA1) reduced steatosis, hepatocellular ballooning, and lobular inflammation, which was confirmed by the decreased NAS score (Figure 4F)
10.1016/j.actbio.2011.12.008 131 MorganW
Homocysteine and methylation markers: The transsulfuration pathway connects methylation to glutathione synthesis, making these markers relevant to antioxidant assessment