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(38) conducted a study in vitro with HDAC inhibitors at specific concentrations (10 nM Romidepsin or 2 M Vorinostat)

Moreover, PBPK models can incorporate physiological, preclinical, and clinical data into the model to predict drug exposure during pregnancy [140,141]

Mitochondrial activities such as the dihydroorotate dehydrogenase, -oxidation of fatty acids, and mitochondrial glycerol-3-phosphate dehydrogenase contribute also to the increase in CoQH 2 levels (Alcazar-Fabra et al., 1A)

References Sung, H

The source of VIC is an important factor, and its levels in the blood must be constantly monitored to determine the impact of VIC on the prevention of cardiovascular disease [52]

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