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Freezing BAC water disrupts the homogeneous distribution of benzyl alcohol in the solution

Aged C57BL/6J mice (18-24 months) : more naturalistic model, slow but robust, ideal for long-term studies on Semax or Selank

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The addition of exogenous IGF-1 (50100 ng ml 1 ) caused a dose-dependent enhancement in the expression of the cytotoxic effector gene PRF1 , but no statistically significant differences could be detected for the mRNA levels of GzmB and IFNG in our experiments (Fig

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Conclusion In this work, we introduced a plastic-based, physiologically relevant BBB platform, which enables to investigate drug permeability and efficacy against cancer tissue models