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In diseases resulting in large bile duct obstruction, extrahepatic and intrahepatic biliary dilatation can be identified on imaging studies, especially if the bilirubin concentration is more than 10 mg/dL and the patient has had jaundice for more than 2 weeks

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Emerging preclinical data suggests it supports extracellular matrix remodeling and anti-inflammatory signaling relevant to intestinal tissue, but it is not as gut-specific in the literature as BPC-157 or KPV

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Monitoring: Clinical response assessment rather than routine serum B12 measurement, as levels remain elevated following injection regardless of tissue adequacy