As an example, Liu and co-workers designed a Fe 2+ -contained and PEG-modified nanocatalyst reacting with overexpressed H 2 O 2 to generate sufficient OH, which is able to kill tumor cells (Huo et al., 2019)
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They describe what is being studied , not proven benefits, approved uses, or promised results
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Concurrently, it oxidizes NANOG/OCT4, remodels the epigenome, degrades membrane lipid rafts, and reverses EMT, stripping CSCs of their self-renewal and tumorigenic capabilities ( Interestingly, CSCs are both sensitive and resistant to ferroptosis
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