Inhibition of lipogenesis AOD-9604 not only breaks down existing fat, but also brakes the formation of new fat
In AP, the abnormal activation of lipase and the excessive accumulation of fatty acids are significant factors that exacerbate disease severity
187,188,189 In CCl 4 -induced liver injury, deletion of YAP/TAZ in BECs hinders the recruitment of phagocytic macrophages, impairing necrotic cell clearance and ultimately leading to regeneration defects at injury sites
In diabetic cardiomyopathy, energy metabolism in cardiomyocytes may be impaired due to factors such as hyperglycemia and insulin resistance
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