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For the isolated dermal area, GHK-Cu has the more direct evidence, including a topical comparative study in humans with quantified collagen endpoints 1

Coryell PR, Diekman BO, Loeser RF

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The formula attempts to make up for those shortcomings by rounding out an approach to anti-aging that includes certain popular ingredients like quercetin and fisetin, but we still think that the smaller list of all clinically dosed ingredients from Innerbody Labs will yeild better results for most people

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Moreover, rotenone induces astrogliosis and alterations in the expression of g-tubulin, signal transducer and activator of transcription 3 (STAT3), and connexin 43 in astrocytes [70, 72, 74]