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Glutathione is the most powerful antioxidant that is present in the body and is known as the master antioxidant

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This decline is one of the mechanisms behind the fatigue, cognitive slowing, and reduced physical resilience that patients often attribute to just getting older. A comprehensive review published in Cell Metabolism documenting the age-related decline in NAD levels and the downstream effects on mitochondrial function, cellular repair, and energy metabolism across tissue types

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However, binding and enzyme inhibition studies revealed a 100-fold more potent affinity for GSTO1 than PDI