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Many users report feeling an improvement in energy levels and a reduction in symptoms like nerve pain or tingling within a few days to a week of starting treatment, depending on the severity of their deficiency or condition

Extended protocols beyond typical 8-12 week durations appear safe based on available evidence

If applied locally via injection, as was done in the study, there is also a risk of structural damage as the needle could break the fragile external walls that protect the discs

Why B12 Supplements May Affect Your Bowels When gastrointestinal symptoms occur with B12 supplementation, several factors may be responsible