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2 Volek JS, Kraemer WJ, Rubin MR, et al

15 Because dysregulation of insulin signaling has been implicated in the pathogenesis of adult acne, it is thought that supplementation with the probiotic strain Lactobacillus rhamnosus SP1 (LSP1) normalizes skin expression of genes involved in insulin signaling and subsequently improves the appearance of adult acne

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Furthermore, GPX4 contributes to mitochondrial clearance in precursors of erythrocytes and GPX4-deficient erythropoiesis is inefficient and associated with abnormal reticulocyte maturation [179]

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