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It's all animals." This applies to TB-500 as well

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While the diagnosis is primarily based clinically on the history and presence of a culprit medication, EGD may be considered if patients have severe or alarm symptoms or symptoms that last beyond 1 week after use of the medication was discontinued

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Some biomarkers, for example the accumulation of phospho-tau proteins, or the decrease in A42 levels in the CSF, serve as excellent diagnostic markers but may be less valuable as evaluation tools for therapeutic development