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However, considering that the human bodys endogenous antioxidant system is not sufficient, the human body can hardly produce nonenzymatic antioxidants, so it depends on exogenous nonenzymatic antioxidants, such as mineral elements, nutritional antioxidants, phytochemicals, cytoprotectants and synthetic compounds (Table 1) [34, 36]

55 JiH.YiQ.ChenL.WongL.LiuY.XuG.et al (2020)

The effect size, though favorable, was modest, raising questions about whether the observed changes would be perceived as meaningful in a clinical setting

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Deeper, bigger changes like reduced pigmentation, improved skin tone, and stronger immunity typically show up around the 6 to 8-week mark

This suggests that chronically elevated arousal in AnxDs may increase neurometabolic demand for choline compounds without a proportionate increase in brain uptake, leading to reduced tCho levels