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2.4 Study selection, eligibility criteria, and data extraction Reviewers underwent training at each step of the process, and a pilot screening was conducted to ensure consistency in applying the eligibility criteria

Like most side effects of weight-loss medications, it may pass with time, but it can be a sign of more significant issues such as kidney complications

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The Grading of Recommendation, Assessment, Development, and Evaluation (GRADE) tool was used to assess the certainty of the evidence for the two primary biochemical outcomesserum vitamin B12 concentration increase and homocysteine reductionacross all included studies, and separately for randomised controlled trials (RCTs) and observational studies

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Allergies and Conditions Individuals with known allergies must consult a healthcare provider before opting for B12 injections to avoid any adverse reactions