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Hydrogen sulfide (H 2 S), a gaseous signaling molecule produced by some cells within the body, acts as a vasodilator (relaxes blood vessels) and thus may have cardioprotective properties (51, 52)

The PCA plot exhibits clear separation among the three conditions, with distinct clustering of the control (blue), 0.03-M CDDP-treated (red), and 3-M CDDP-treated (green) groups

These are far less accessible and far less commonly performed than verapamil

Animals were monitored daily for clinical signs, with regular measurements of body weight, food consumption and vital signs

Because they work so hard, they are highly susceptible to damage from toxins and environmental pollutants

However, issues with hepatocyte acquisition, preservation, and immunological rejection limit its feasibility