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Beyond primary mitochondrial disorders, in liver mitochondria, MT localizes to the intermembrane space and can be imported into the organelle, where its N-terminal -domain delivers zinc to the electron transport chain, inhibiting respiration in a tissue-specific and zinc-dependent manner

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As a result, patients often complain about LBP postoperatively with a high recurrence risk of neurological symptoms

This ability was caused by a reduction in the accumulation of uremic toxins (Soulage 2013

More than half reached a body mass index below 30, compared with roughly one in ten on placebo

Possible modest effects on dihydrotestosterone (DHT) activity , suggested by some in vitro studies