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The induction of defense response occurred in the early infection phase at 3 days post-inoculation and it was consistent with lower levels of disease severity in resistant cultivars (Veluchamy and Panthee, 2015)

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To assess small intestinal transit, we employed an activated carbon gavage test 17 , which revealed a significant, dose-dependent reduction in the small intestinal transit rate in morphine-treated mice compared to saline-treated controls (Fig