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At present, there are four kinds of western medicines used clinically to treat RA: nonsteroidal anti-inflammatory drugs, glucocorticoids, anti-rheumatic drugs and biological agents

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Results Fragment-based drug design and chemistry Utilizing actives identified in a quantitative high-throughput screen against Schistosoma mansoni TGR 20,35 , 92 commercially available low molecular weight (MW) compounds/fragments were tested by X-ray crystallography 33,34,36

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