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Copper and its alloys are present in numerous articles of everyday use, such as coinage, tools, jewelry, and dental materials, thus it comes in regular, sometimes extended contact with skin

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Slow IV push: used for lower doses, given over several minutes

Significantly, as shown in Figure 6 in their Extended Data (9), Gordon et al

1% GHK-CU Copper Tripeptide Serum w/ Hyaluronic Acid | Niacinamide Purified Water (Aqua), Hyaluronic Acid, Saccharomyces-Copper Ferment, Niacinamide, Copper Peptide GHK-Cu, Palmitoyl Tripeptide-5 (Syn Coll), Palmitoyl Tripeptide-38 (Matrixyl Synthe 6), Gluconolactone (Natural Preservative), Glycerine has been tested and proven to improve many skin conditions resulting from aging skin - Proven to reduce wrinkle depth, tighten and lift skin, rebuild collagen loss and plump skin

Tong SYC, Davis JS, Eichenberger E, Holland TL, Fowler VG., Jr