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In an open-label phase II trial, curcumin treatment (8 g/day) in combination with the anticancer drug gemcitabine was associated with severe abdominal pain in 7 out of 17 patients with advanced pancreatic cancer, leading to the treatment being discontinued in five patients while curcumin dosage was reduced to 4 g/day in two patients (79)

doi:10.1111/all.70030

The volume drawn determines the final concentration (see dilution charts below)

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For example, changes in peripheral metabolites may play a role in clinical presentation and outcome during the early course of SZ (Yao et al., 2012)