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Long-term inhibition of core pathways like GPX4 carries unknown risks, while targeting upstream regulators like Nrf2 harbors potential off-target effects due to their broad biological functions

Park JH, Yoon YK, Choi SO, Prausnitz MR, Allen MG

Concentration (mg/ml) = Total peptide (mg) / Total water (ml) For a 5mg vial: 5mg + 1ml water = 5mg/ml 5mg + 2ml water = 2.5mg/ml 5mg + 2.5ml water = 2mg/ml 5mg + 3ml water = 1.67mg/ml Each concentration creates different syringe measurements for the same dose

The P53 pathway: what questions remain to be explored

Following treatment with GHK-Cu, this index was significantly reduced (Figure 2C)

2020;2:e41827